BDBM50355667 CHEMBL1910980

SMILES: NC(=O)[C@H](Cc1ccc(cc1)N=C(N)CF)NC(=O)c1ccccc1

InChI Key: InChIKey=SDHVJUNLHOVWRK-HNNXBMFYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50355667   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
protein-arginine deiminase type-4 (Homo sapiens (Human))	BDBM50355667 (CHEMBL1910980) Show SMILES NC(=O)[C@H](Cc1ccc(cc1)N=C(N)CF)NC(=O)c1ccccc1 |r,w:11.11| Show InChI InChI=1S/C18H19FN4O2/c19-11-16(20)22-14-8-6-12(7-9-14)10-15(17(21)24)23-18(25)13-4-2-1-3-5-13/h1-9,15H,10-11H2,(H2,20,22)(H2,21,24)(H,23,25)/t15-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.10E+5	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Irreversible inhibition of PAD4 assessed as hydrolysis of benzoyl-L-arginine ethyl ester preincubated for 15 mins measured after 15 mins by fluoromet...				J Med Chem 54: 6919-35 (2011) Article DOI: 10.1021/jm2008985 BindingDB Entry DOI: 10.7270/Q24F1R4M
					More data for this Ligand-Target Pair