BDBM50355748 CHEMBL1911144

SMILES: CC(C)([C@H]1c2ccccc2Oc2nc(ccc12)-c1ccccc1)C(=O)Nc1nncs1

InChI Key: InChIKey=DJPCZSGKILEQOC-FQEVSTJZSA-N

Data: 1 KI  4 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50355748   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50355748 (CHEMBL1911144) Show SMILES CC(C)([C@H]1c2ccccc2Oc2nc(ccc12)-c1ccccc1)C(=O)Nc1nncs1 |r| Show InChI InChI=1S/C24H20N4O2S/c1-24(2,22(29)27-23-28-25-14-31-23)20-16-10-6-7-11-19(16)30-21-17(20)12-13-18(26-21)15-8-4-3-5-9-15/h3-14,20H,1-2H3,(H,27,28,29)/t20-/m0/s1	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	7.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company Curated by ChEMBL					Assay Description Displacement of GS-red from glucocorticoid receptor by fluorescence polarization assay				J Med Chem 54: 7318-33 (2011) Article DOI: 10.1021/jm200879j BindingDB Entry DOI: 10.7270/Q2W0969M
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50355748 (CHEMBL1911144) Show SMILES CC(C)([C@H]1c2ccccc2Oc2nc(ccc12)-c1ccccc1)C(=O)Nc1nncs1 |r| Show InChI InChI=1S/C24H20N4O2S/c1-24(2,22(29)27-23-28-25-14-31-23)20-16-10-6-7-11-19(16)30-21-17(20)12-13-18(26-21)15-8-4-3-5-9-15/h3-14,20H,1-2H3,(H,27,28,29)/t20-/m0/s1	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.50E+3	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company Curated by ChEMBL					Assay Description Transrepression activity at glucocorticoid receptor alpha in phorbol myristate acetate-stimulated human A549 cells assessed as inhibition of AP1 resp...				J Med Chem 54: 7318-33 (2011) Article DOI: 10.1021/jm200879j BindingDB Entry DOI: 10.7270/Q2W0969M
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50355748 (CHEMBL1911144) Show SMILES CC(C)([C@H]1c2ccccc2Oc2nc(ccc12)-c1ccccc1)C(=O)Nc1nncs1 |r| Show InChI InChI=1S/C24H20N4O2S/c1-24(2,22(29)27-23-28-25-14-31-23)20-16-10-6-7-11-19(16)30-21-17(20)12-13-18(26-21)15-8-4-3-5-9-15/h3-14,20H,1-2H3,(H,27,28,29)/t20-/m0/s1	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	187	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company Curated by ChEMBL					Assay Description Transactivation activity at GR-alpha in human NP1 Hela cells assessed as inhibition of GAL4-DBD after 20 hrs by luciferase reporter gene assay				J Med Chem 54: 7318-33 (2011) Article DOI: 10.1021/jm200879j BindingDB Entry DOI: 10.7270/Q2W0969M
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50355748 (CHEMBL1911144) Show SMILES CC(C)([C@H]1c2ccccc2Oc2nc(ccc12)-c1ccccc1)C(=O)Nc1nncs1 |r| Show InChI InChI=1S/C24H20N4O2S/c1-24(2,22(29)27-23-28-25-14-31-23)20-16-10-6-7-11-19(16)30-21-17(20)12-13-18(26-21)15-8-4-3-5-9-15/h3-14,20H,1-2H3,(H,27,28,29)/t20-/m0/s1	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company Curated by ChEMBL					Assay Description Transactivation activity at GR-alpha in human NP1 Hela cells assessed as induction of GAL4-DBD after 20 hrs by luciferase reporter gene assay				J Med Chem 54: 7318-33 (2011) Article DOI: 10.1021/jm200879j BindingDB Entry DOI: 10.7270/Q2W0969M
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50355748 (CHEMBL1911144) Show SMILES CC(C)([C@H]1c2ccccc2Oc2nc(ccc12)-c1ccccc1)C(=O)Nc1nncs1 |r| Show InChI InChI=1S/C24H20N4O2S/c1-24(2,22(29)27-23-28-25-14-31-23)20-16-10-6-7-11-19(16)30-21-17(20)12-13-18(26-21)15-8-4-3-5-9-15/h3-14,20H,1-2H3,(H,27,28,29)/t20-/m0/s1	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>5.00E+3	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company Curated by ChEMBL					Assay Description Transactivation activity at glucocorticoid receptor alpha human 13D3/Huh7 cells assessed as induction of TAT activity after 4 hrs by spectrophotometr...				J Med Chem 54: 7318-33 (2011) Article DOI: 10.1021/jm200879j BindingDB Entry DOI: 10.7270/Q2W0969M
					More data for this Ligand-Target Pair