BDBM50355906 CHEMBL1910192

SMILES: Oc1ccc(cc1)-c1cncc(n1)-c1cc2cc(O)ccc2[nH]1

InChI Key: InChIKey=KBPRLLIVAKEOFQ-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50355906   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A (RAT)	BDBM50355906 (CHEMBL1910192) Show SMILES Oc1ccc(cc1)-c1cncc(n1)-c1cc2cc(O)ccc2[nH]1 Show InChI InChI=1S/C18H13N3O2/c22-13-3-1-11(2-4-13)17-9-19-10-18(21-17)16-8-12-7-14(23)5-6-15(12)20-16/h1-10,20,22-23H	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	340	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ d'Orl£ans Curated by ChEMBL					Assay Description Inhibition of rat recombinant GST-fused DYRK1A expressed in Escherichia coli using myelin protein and [33P-gamma]-ATP after 30 mins by scintillation ...				Eur J Med Chem 46: 5416-34 (2011) Article DOI: 10.1016/j.ejmech.2011.08.048 BindingDB Entry DOI: 10.7270/Q2T1542V
					More data for this Ligand-Target Pair
Cyclin-Dependent Kinase 5 (CDK5) (Homo sapiens (Human))	BDBM50355906 (CHEMBL1910192) Show SMILES Oc1ccc(cc1)-c1cncc(n1)-c1cc2cc(O)ccc2[nH]1 Show InChI InChI=1S/C18H13N3O2/c22-13-3-1-11(2-4-13)17-9-19-10-18(21-17)16-8-12-7-14(23)5-6-15(12)20-16/h1-10,20,22-23H	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ d'Orl£ans Curated by ChEMBL					Assay Description Inhibition of human recombinant CDK5/p25 using histone H1 and [33P-gamma]-ATP after 30 mins by scintillation counting				Eur J Med Chem 46: 5416-34 (2011) Article DOI: 10.1016/j.ejmech.2011.08.048 BindingDB Entry DOI: 10.7270/Q2T1542V
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 (Sus scrofa)	BDBM50355906 (CHEMBL1910192) Show SMILES Oc1ccc(cc1)-c1cncc(n1)-c1cc2cc(O)ccc2[nH]1 Show InChI InChI=1S/C18H13N3O2/c22-13-3-1-11(2-4-13)17-9-19-10-18(21-17)16-8-12-7-14(23)5-6-15(12)20-16/h1-10,20,22-23H	PDB MMDB Reactome pathway KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ d'Orl£ans Curated by ChEMBL					Assay Description Inhibition of porcine brain GSK3-beta assessed as incorporation of [gamma-33P]-ATP into YRRAAVPPSPSLSRHSSPHQSpEDEEE substrate after 30 mins by scinti...				Eur J Med Chem 46: 5416-34 (2011) Article DOI: 10.1016/j.ejmech.2011.08.048 BindingDB Entry DOI: 10.7270/Q2T1542V
					More data for this Ligand-Target Pair