BDBM50356258 CHEMBL1910689

SMILES: C\N=C1/S\C(=C/c2cc(C)n(Cc3c(F)cccc3F)c2C)C(=O)N1C

InChI Key: InChIKey=LFLNRZOGPMTFGU-UYMBLXCVSA-N

Data: 3 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50356258   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sphingosine 1-phosphate receptor 4 (Homo sapiens (Human))	BDBM50356258 (CHEMBL1910689) Show SMILES C\N=C1/S\C(=C/c2cc(C)n(Cc3c(F)cccc3F)c2C)C(=O)N1C Show InChI InChI=1S/C19H19F2N3OS/c1-11-8-13(9-17-18(25)23(4)19(22-3)26-17)12(2)24(11)10-14-15(20)6-5-7-16(14)21/h5-9H,10H2,1-4H3/b17-9-,22-19-	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	92	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Agonist activity at S1P4 receptor in human U2OS cells expressing VP16-GAL4 transcriptional factor and beta-arrestin/TEV protease fusion protein asses...				Bioorg Med Chem Lett 21: 6739-45 (2011) Article DOI: 10.1016/j.bmcl.2011.09.049 BindingDB Entry DOI: 10.7270/Q2736RBP
					More data for this Ligand-Target Pair
Sphingosine 1-phosphate receptor 5 (Homo sapiens (Human))	BDBM50356258 (CHEMBL1910689) Show SMILES C\N=C1/S\C(=C/c2cc(C)n(Cc3c(F)cccc3F)c2C)C(=O)N1C Show InChI InChI=1S/C19H19F2N3OS/c1-11-8-13(9-17-18(25)23(4)19(22-3)26-17)12(2)24(11)10-14-15(20)6-5-7-16(14)21/h5-9H,10H2,1-4H3/b17-9-,22-19-	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	34	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Agonist activity at S1P5 receptor				Bioorg Med Chem Lett 21: 6739-45 (2011) Article DOI: 10.1016/j.bmcl.2011.09.049 BindingDB Entry DOI: 10.7270/Q2736RBP
					More data for this Ligand-Target Pair
Sphingosine 1-phosphate receptor 1 (Homo sapiens (Human))	BDBM50356258 (CHEMBL1910689) Show SMILES C\N=C1/S\C(=C/c2cc(C)n(Cc3c(F)cccc3F)c2C)C(=O)N1C Show InChI InChI=1S/C19H19F2N3OS/c1-11-8-13(9-17-18(25)23(4)19(22-3)26-17)12(2)24(11)10-14-15(20)6-5-7-16(14)21/h5-9H,10H2,1-4H3/b17-9-,22-19-	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	34	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Agonist activity at S1P1 receptor				Bioorg Med Chem Lett 21: 6739-45 (2011) Article DOI: 10.1016/j.bmcl.2011.09.049 BindingDB Entry DOI: 10.7270/Q2736RBP
					More data for this Ligand-Target Pair