BindingDB logo
myBDB logout

null

SMILES: OC(CN(C(=O)c1ccccc1)c1ccc(cc1)C(F)(F)F)Cn1c2ccccc2c2ccccc12

InChI Key: InChIKey=WRZWNGDNMKKPBC-UHFFFAOYSA-N

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50356526   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Beta-secretase 1


(Homo sapiens (Human))
BDBM50356526
PNG
(CHEMBL1909687)
Show SMILES OC(CN(C(=O)c1ccccc1)c1ccc(cc1)C(F)(F)F)Cn1c2ccccc2c2ccccc12
Show InChI InChI=1S/C29H23F3N2O2/c30-29(31,32)21-14-16-22(17-15-21)33(28(36)20-8-2-1-3-9-20)18-23(35)19-34-26-12-6-4-10-24(26)25-11-5-7-13-27(25)34/h1-17,23,35H,18-19H2
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>1.00E+4n/an/an/an/an/an/a



Universit£ di Pisa

Curated by ChEMBL


Assay Description
Inhibition of BACE1 by fluorescence-based assay


Bioorg Med Chem Lett 21: 6657-61 (2011)


Article DOI: 10.1016/j.bmcl.2011.09.064
BindingDB Entry DOI: 10.7270/Q2ST7Q7H
More data for this
Ligand-Target Pair