BDBM50356626 CHEMBL1914699

SMILES: CN1C2CCC1[C@@H](CNc1cccc(F)n1)[C@H](C2)c1ccc(Cl)cc1

InChI Key: InChIKey=QWGVIOYTQRTWPO-UMQBVGHOSA-N

Data: 3 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50356626   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium-dependent dopamine transporter (Homo sapiens (Human))	BDBM50356626 (CHEMBL1914699) Show SMILES CN1C2CCC1[C@@H](CNc1cccc(F)n1)[C@H](C2)c1ccc(Cl)cc1 |r,TLB:0:1:16.6.17:3.4| Show InChI InChI=1S/C20H23ClFN3/c1-25-15-9-10-18(25)17(12-23-20-4-2-3-19(22)24-20)16(11-15)13-5-7-14(21)8-6-13/h2-8,15-18H,9-12H2,1H3,(H,23,24)/t15?,16-,17+,18?/m1/s1	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	4.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Key Laboratory of Radiopharmaceuticals (Beijing Normal University) Curated by ChEMBL					Assay Description Displacement of [125I]-IPT from DAT transfected in pig LLC-PK1 cells by radioligand competition binding assay				Bioorg Med Chem Lett 21: 2962-5 (2011) Article DOI: 10.1016/j.bmcl.2011.03.051 BindingDB Entry DOI: 10.7270/Q2WM1DT0
					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Homo sapiens (Human))	BDBM50356626 (CHEMBL1914699) Show SMILES CN1C2CCC1[C@@H](CNc1cccc(F)n1)[C@H](C2)c1ccc(Cl)cc1 |r,TLB:0:1:16.6.17:3.4| Show InChI InChI=1S/C20H23ClFN3/c1-25-15-9-10-18(25)17(12-23-20-4-2-3-19(22)24-20)16(11-15)13-5-7-14(21)8-6-13/h2-8,15-18H,9-12H2,1H3,(H,23,24)/t15?,16-,17+,18?/m1/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	21	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Key Laboratory of Radiopharmaceuticals (Beijing Normal University) Curated by ChEMBL					Assay Description Displacement of [125I]-IDAM from SERT transfected in pig LLC-PK1 cells by radioligand competition binding assay				Bioorg Med Chem Lett 21: 2962-5 (2011) Article DOI: 10.1016/j.bmcl.2011.03.051 BindingDB Entry DOI: 10.7270/Q2WM1DT0
					More data for this Ligand-Target Pair
Sodium-dependent noradrenaline transporter (Homo sapiens (Human))	BDBM50356626 (CHEMBL1914699) Show SMILES CN1C2CCC1[C@@H](CNc1cccc(F)n1)[C@H](C2)c1ccc(Cl)cc1 |r,TLB:0:1:16.6.17:3.4| Show InChI InChI=1S/C20H23ClFN3/c1-25-15-9-10-18(25)17(12-23-20-4-2-3-19(22)24-20)16(11-15)13-5-7-14(21)8-6-13/h2-8,15-18H,9-12H2,1H3,(H,23,24)/t15?,16-,17+,18?/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	66	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Key Laboratory of Radiopharmaceuticals (Beijing Normal University) Curated by ChEMBL					Assay Description Displacement of [125I]-INXT from NET transfected in pig LLC-PK1 cells by radioligand competition binding assay				Bioorg Med Chem Lett 21: 2962-5 (2011) Article DOI: 10.1016/j.bmcl.2011.03.051 BindingDB Entry DOI: 10.7270/Q2WM1DT0
					More data for this Ligand-Target Pair