BDBM50356817 CHEMBL1914783

SMILES: CN[C@@H]1CCN(C1)c1nc(N)nc2c3cc(ccc3oc12)C(F)(F)F

InChI Key: InChIKey=SGVHAMXFQVQZHT-SECBINFHSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50356817   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histamine H4 receptor (Homo sapiens (Human))	BDBM50356817 (CHEMBL1914783) Show SMILES CN[C@@H]1CCN(C1)c1nc(N)nc2c3cc(ccc3oc12)C(F)(F)F |r| Show InChI InChI=1S/C16H16F3N5O/c1-21-9-4-5-24(7-9)14-13-12(22-15(20)23-14)10-6-8(16(17,18)19)2-3-11(10)25-13/h2-3,6,9,21H,4-5,7H2,1H3,(H2,20,22,23)/t9-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research& Development Curated by ChEMBL					Assay Description Displacement of [3H]histamine from recombinant human histamine H4 receptor				Bioorg Med Chem Lett 21: 6577-81 (2011) Article DOI: 10.1016/j.bmcl.2011.08.014 BindingDB Entry DOI: 10.7270/Q2CN749X
					More data for this Ligand-Target Pair