BDBM50356945 CHEMBL1916053

SMILES: CC1=CC[C@@H](NS(=O)(=O)c2ccc(Oc3ccc(Cl)cc3)cc2)C(=O)N(O)C1

InChI Key: InChIKey=RHVLZBAJLKIMQO-GOSISDBHSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50356945   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
72 kDa type IV collagenase (Homo sapiens (Human))	BDBM50356945 (CHEMBL1916053) Show SMILES CC1=CC[C@@H](NS(=O)(=O)c2ccc(Oc3ccc(Cl)cc3)cc2)C(=O)N(O)C1 |r,t:1| Show InChI InChI=1S/C19H19ClN2O5S/c1-13-2-11-18(19(23)22(24)12-13)21-28(25,26)17-9-7-16(8-10-17)27-15-5-3-14(20)4-6-15/h2-10,18,21,24H,11-12H2,1H3/t18-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research& Development Curated by ChEMBL					Assay Description Inhibition of full length human MMP2 (amino acids 1 to 660) using acetyl-Cys(Eu)-Pro-Leu-Gly-Leu-Lys-(QSY7)-Ala-Arg-amide as substrate preincubated f...				Bioorg Med Chem Lett 21: 6485-90 (2011) Article DOI: 10.1016/j.bmcl.2011.08.068 BindingDB Entry DOI: 10.7270/Q2BP0353
					More data for this Ligand-Target Pair
Matrix metalloproteinase-9 (Homo sapiens (Human))	BDBM50356945 (CHEMBL1916053) Show SMILES CC1=CC[C@@H](NS(=O)(=O)c2ccc(Oc3ccc(Cl)cc3)cc2)C(=O)N(O)C1 |r,t:1| Show InChI InChI=1S/C19H19ClN2O5S/c1-13-2-11-18(19(23)22(24)12-13)21-28(25,26)17-9-7-16(8-10-17)27-15-5-3-14(20)4-6-15/h2-10,18,21,24H,11-12H2,1H3/t18-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.30	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research& Development Curated by ChEMBL					Assay Description Inhibition of human MMP9 catalytic domain (amino acids 107 to 446) using acetyl-Cys(Eu)-Pro-Leu-Gly-Leu-Lys-(QSY7)-Ala-Arg-amide as substrate preincu...				Bioorg Med Chem Lett 21: 6485-90 (2011) Article DOI: 10.1016/j.bmcl.2011.08.068 BindingDB Entry DOI: 10.7270/Q2BP0353
					More data for this Ligand-Target Pair