BDBM50357245 CHEMBL1916481

SMILES: CCCOCCn1c2cc(nnc2c(N[C@H](C)C(O)=O)nc1=O)-c1ccc(OC)nc1

InChI Key: InChIKey=HOKCYKHLUVOXNW-GFCCVEGCSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50357245   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cGMP-specific 3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM50357245 (CHEMBL1916481) Show SMILES CCCOCCn1c2cc(nnc2c(N[C@H](C)C(O)=O)nc1=O)-c1ccc(OC)nc1 |r| Show InChI InChI=1S/C20H24N6O5/c1-4-8-31-9-7-26-15-10-14(13-5-6-16(30-3)21-11-13)24-25-17(15)18(23-20(26)29)22-12(2)19(27)28/h5-6,10-12H,4,7-9H2,1-3H3,(H,27,28)(H,22,23,29)/t12-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.130	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of PDE5				Bioorg Med Chem Lett 21: 6348-52 (2011) Article DOI: 10.1016/j.bmcl.2011.08.106 BindingDB Entry DOI: 10.7270/Q2J67HB0
					More data for this Ligand-Target Pair