BDBM50357246 CHEMBL1916480

SMILES: CCOCCn1c2cc(nnc2c(NCC(=O)N(C)C)nc1=O)-c1ccc(OC)nc1

InChI Key: InChIKey=QSYMRYLKWWVVIA-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50357246   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cGMP-specific 3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM50357246 (CHEMBL1916480) Show SMILES CCOCCn1c2cc(nnc2c(NCC(=O)N(C)C)nc1=O)-c1ccc(OC)nc1 Show InChI InChI=1S/C20H25N7O4/c1-5-31-9-8-27-15-10-14(13-6-7-16(30-4)21-11-13)24-25-18(15)19(23-20(27)29)22-12-17(28)26(2)3/h6-7,10-11H,5,8-9,12H2,1-4H3,(H,22,23,29)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.5	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of PDE5				Bioorg Med Chem Lett 21: 6348-52 (2011) Article DOI: 10.1016/j.bmcl.2011.08.106 BindingDB Entry DOI: 10.7270/Q2J67HB0
					More data for this Ligand-Target Pair