BDBM50357247 CHEMBL1916479

SMILES: COc1ccc(cn1)-c1cc2n(CCOCC(F)(F)F)c(=O)nc(NCC(=O)N(C)C)c2nn1

InChI Key: InChIKey=ZWWZYUASXZMMIK-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50357247   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cGMP-specific 3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM50357247 (CHEMBL1916479) Show SMILES COc1ccc(cn1)-c1cc2n(CCOCC(F)(F)F)c(=O)nc(NCC(=O)N(C)C)c2nn1 Show InChI InChI=1S/C20H22F3N7O4/c1-29(2)16(31)10-25-18-17-14(30(19(32)26-18)6-7-34-11-20(21,22)23)8-13(27-28-17)12-4-5-15(33-3)24-9-12/h4-5,8-9H,6-7,10-11H2,1-3H3,(H,25,26,32)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.380	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of PDE5				Bioorg Med Chem Lett 21: 6348-52 (2011) Article DOI: 10.1016/j.bmcl.2011.08.106 BindingDB Entry DOI: 10.7270/Q2J67HB0
					More data for this Ligand-Target Pair