BDBM50357248 CHEMBL1916478

SMILES: CCCOCCn1c2cc(nnc2c(NCC(=O)N(C)C)nc1=O)-c1ccc(OC)nc1

InChI Key: InChIKey=CUZPLGMPQHOVMB-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50357248   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cGMP-specific 3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM50357248 (CHEMBL1916478) Show SMILES CCCOCCn1c2cc(nnc2c(NCC(=O)N(C)C)nc1=O)-c1ccc(OC)nc1 Show InChI InChI=1S/C21H27N7O4/c1-5-9-32-10-8-28-16-11-15(14-6-7-17(31-4)22-12-14)25-26-19(16)20(24-21(28)30)23-13-18(29)27(2)3/h6-7,11-12H,5,8-10,13H2,1-4H3,(H,23,24,30)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.440	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of PDE5				Bioorg Med Chem Lett 21: 6348-52 (2011) Article DOI: 10.1016/j.bmcl.2011.08.106 BindingDB Entry DOI: 10.7270/Q2J67HB0
					More data for this Ligand-Target Pair