BDBM50357256 CHEMBL1916301

SMILES: CCCOCCn1c2cc(nnc2c(NCCO)nc1=O)-c1ccc(OC)nc1

InChI Key: InChIKey=PALJVDOUOJINDI-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50357256   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cGMP-specific 3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM50357256 (CHEMBL1916301) Show SMILES CCCOCCn1c2cc(nnc2c(NCCO)nc1=O)-c1ccc(OC)nc1 Show InChI InChI=1S/C19H24N6O4/c1-3-9-29-10-7-25-15-11-14(13-4-5-16(28-2)21-12-13)23-24-17(15)18(20-6-8-26)22-19(25)27/h4-5,11-12,26H,3,6-10H2,1-2H3,(H,20,22,27)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.220	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of PDE5				Bioorg Med Chem Lett 21: 6348-52 (2011) Article DOI: 10.1016/j.bmcl.2011.08.106 BindingDB Entry DOI: 10.7270/Q2J67HB0
					More data for this Ligand-Target Pair