BDBM50357267 CHEMBL1916493
SMILES: COc1ccccc1Cn1ccc(NCCc2cnc[nH]2)nc1=O
InChI Key: InChIKey=ZQXUXSWEXYSYLK-UHFFFAOYSA-N
Data: 2 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Histamine H4 receptor (Homo sapiens (Human)) | BDBM50357267 (CHEMBL1916493) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | 1.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc. Curated by ChEMBL | Assay Description Displacement of [3H]histamine from human histamine H4 receptor expressed in CHO cells after 90 mins by scintillation counting technique | Bioorg Med Chem Lett 21: 6591-5 (2011) Article DOI: 10.1016/j.bmcl.2011.07.114 BindingDB Entry DOI: 10.7270/Q2DF6RNQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Histamine H4 receptor (Homo sapiens (Human)) | BDBM50357267 (CHEMBL1916493) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | >2.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc. Curated by ChEMBL | Assay Description Antagonist activity at human histamine H4 receptor by functional assay | Bioorg Med Chem Lett 21: 6591-5 (2011) Article DOI: 10.1016/j.bmcl.2011.07.114 BindingDB Entry DOI: 10.7270/Q2DF6RNQ | |||||||||||
More data for this Ligand-Target Pair |