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BDBM50357270 CHEMBL1916496

SMILES: CC(C)(C)CCNc1cc(N[C@H]2CCN(Cc3cccc(F)c3O)C2)ncn1

InChI Key: InChIKey=RBSBBGZWUIWZIJ-INIZCTEOSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50357270   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Histamine H4 receptor


(Homo sapiens (Human))		BDBM50357270
PNG
(CHEMBL1916496)
Show SMILES CC(C)(C)CCNc1cc(N[C@H]2CCN(Cc3cccc(F)c3O)C2)ncn1 |r|
Show InChI InChI=1S/C21H30FN5O/c1-21(2,3)8-9-23-18-11-19(25-14-24-18)26-16-7-10-27(13-16)12-15-5-4-6-17(22)20(15)28/h4-6,11,14,16,28H,7-10,12-13H2,1-3H3,(H2,23,24,25,26)/t16-/m0/s1
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PC cid
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Article
PubMed
 2.00E+4n/an/an/an/an/an/an/an/a



Pfizer Inc.

Curated by ChEMBL


Assay Description
Displacement of [3H]histamine from human histamine H4 receptor expressed in CHO cells after 90 mins by scintillation counting technique

Bioorg Med Chem Lett 21: 6591-5 (2011)


Article DOI: 10.1016/j.bmcl.2011.07.114
BindingDB Entry DOI: 10.7270/Q2DF6RNQ
More data for this
Ligand-Target Pair