BDBM50357318 CHEMBL1916717

SMILES: CCN(C(=O)\C=C\CN(C)C)c1cc2c(cc1OC)nc(Nc1ccccc1C)c1cncn21

InChI Key: InChIKey=OJZKUAGKHXFNTK-FMIVXFBMSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50357318   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase Lyn (Homo sapiens (Human))	BDBM50357318 (CHEMBL1916717) Show SMILES CCN(C(=O)\C=C\CN(C)C)c1cc2c(cc1OC)nc(Nc1ccccc1C)c1cncn21 Show InChI InChI=1S/C26H30N6O2/c1-6-31(25(33)12-9-13-30(3)4)22-15-21-20(14-24(22)34-5)29-26(23-16-27-17-32(21)23)28-19-11-8-7-10-18(19)2/h7-12,14-17H,6,13H2,1-5H3,(H,28,29)/b12-9+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	533	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of LYN-A expressed in Sf9 cells after 60 mins by TR-FRET Assay				Bioorg Med Chem Lett 21: 6258-63 (2011) Article DOI: 10.1016/j.bmcl.2011.09.008 BindingDB Entry DOI: 10.7270/Q21836XD
					More data for this Ligand-Target Pair
Tyrosine-protein kinase BTK (Homo sapiens (Human))	BDBM50357318 (CHEMBL1916717) Show SMILES CCN(C(=O)\C=C\CN(C)C)c1cc2c(cc1OC)nc(Nc1ccccc1C)c1cncn21 Show InChI InChI=1S/C26H30N6O2/c1-6-31(25(33)12-9-13-30(3)4)22-15-21-20(14-24(22)34-5)29-26(23-16-27-17-32(21)23)28-19-11-8-7-10-18(19)2/h7-12,14-17H,6,13H2,1-5H3,(H,28,29)/b12-9+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	19.1	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of human full-length BTK expressed in Sf9 cells using FAM-Srctide peptide as substrate after 60 mins by TR-FRET Assay				Bioorg Med Chem Lett 21: 6258-63 (2011) Article DOI: 10.1016/j.bmcl.2011.09.008 BindingDB Entry DOI: 10.7270/Q21836XD
					More data for this Ligand-Target Pair