BDBM50357543 CHEMBL1915161

SMILES: COC(=O)[C@@H]1Cc2c(CN1CC1CC1)[nH]c1ccccc21

InChI Key: InChIKey=NNTYPSPSESLDDC-INIZCTEOSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50357543   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cytochrome P450 19A1 (Homo sapiens (Human))	BDBM50357543 (CHEMBL1915161) Show SMILES COC(=O)[C@@H]1Cc2c(CN1CC1CC1)[nH]c1ccccc21 |r| Show InChI InChI=1S/C17H20N2O2/c1-21-17(20)16-8-13-12-4-2-3-5-14(12)18-15(13)10-19(16)9-11-6-7-11/h2-5,11,16,18H,6-10H2,1H3/t16-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.86E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Hawai'i at Hilo Curated by ChEMBL					Assay Description Inhibition of aromatase after 10 mins preincubation by plate reader relative to control				Bioorg Med Chem 19: 6182-95 (2011) Article DOI: 10.1016/j.bmc.2011.09.020 BindingDB Entry DOI: 10.7270/Q2Z89CTS
					More data for this Ligand-Target Pair