BDBM50357544 CHEMBL1915167

SMILES: COC(=O)[C@@H]1Cc2c(CN1C(=O)NC(C)C)[nH]c1ccccc21

InChI Key: InChIKey=QOMOGWIWTFYRRF-HNNXBMFYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50357544   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cytochrome P450 19A1 (Homo sapiens (Human))	BDBM50357544 (CHEMBL1915167) Show SMILES COC(=O)[C@@H]1Cc2c(CN1C(=O)NC(C)C)[nH]c1ccccc21 |r| Show InChI InChI=1S/C17H21N3O3/c1-10(2)18-17(22)20-9-14-12(8-15(20)16(21)23-3)11-6-4-5-7-13(11)19-14/h4-7,10,15,19H,8-9H2,1-3H3,(H,18,22)/t15-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.73E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Hawai'i at Hilo Curated by ChEMBL					Assay Description Inhibition of aromatase after 10 mins preincubation by plate reader relative to control				Bioorg Med Chem 19: 6182-95 (2011) Article DOI: 10.1016/j.bmc.2011.09.020 BindingDB Entry DOI: 10.7270/Q2Z89CTS
					More data for this Ligand-Target Pair