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BDBM50357552 CHEMBL1915163

SMILES: COC(=O)[C@H]1Cc2c(CN1Cc1ccccc1)[nH]c1ccccc21

InChI Key: InChIKey=JHPBGDBTBGLGOG-LJQANCHMSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50357552   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Nitric Oxide Synthase, inducible


(Mus musculus (mouse))
BDBM50357552
PNG
(CHEMBL1915163)
Show SMILES COC(=O)[C@H]1Cc2c(CN1Cc1ccccc1)[nH]c1ccccc21 |r|
Show InChI InChI=1S/C20H20N2O2/c1-24-20(23)19-11-16-15-9-5-6-10-17(15)21-18(16)13-22(19)12-14-7-3-2-4-8-14/h2-10,19,21H,11-13H2,1H3/t19-/m1/s1
PDB
MMDB

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PC cid
PC sid
UniChem
Article
PubMed
n/an/a 3.29E+4n/an/an/an/an/an/a



University of Hawai'i at Hilo

Curated by ChEMBL


Assay Description
Inhibition of iNOS-mediated nitric oxide production in LPS-stimulated mouse RAW 264.7 cells pretreated 15 mins before LPS challenge measured after 20...


Bioorg Med Chem 19: 6182-95 (2011)


Article DOI: 10.1016/j.bmc.2011.09.020
BindingDB Entry DOI: 10.7270/Q2Z89CTS
More data for this
Ligand-Target Pair