BDBM50357557 CHEMBL1915174

SMILES: COC(=O)[C@H]1Cc2c(CN1C(=O)NC13CC4CC(CC(C4)C1)C3)[nH]c1ccccc21

InChI Key: InChIKey=MZWMPUXEJIICDD-MSQNUCTKSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50357557   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Nitric Oxide Synthase, inducible (Mus musculus (mouse))	BDBM50357557 (CHEMBL1915174) Show SMILES COC(=O)[C@H]1Cc2c(CN1C(=O)NC13CC4CC(CC(C4)C1)C3)[nH]c1ccccc21 |r,TLB:12:13:16.15.20:18,THB:14:15:18:22.13.21,14:13:16.15.20:18,21:13:16:20.19.18,21:19:16:22.14.13| Show InChI InChI=1S/C24H29N3O3/c1-30-22(28)21-9-18-17-4-2-3-5-19(17)25-20(18)13-27(21)23(29)26-24-10-14-6-15(11-24)8-16(7-14)12-24/h2-5,14-16,21,25H,6-13H2,1H3,(H,26,29)/t14?,15?,16?,21-,24?/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.17E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Hawai'i at Hilo Curated by ChEMBL					Assay Description Inhibition of iNOS-mediated nitric oxide production in LPS-stimulated mouse RAW 264.7 cells pretreated 15 mins before LPS challenge measured after 20...				Bioorg Med Chem 19: 6182-95 (2011) Article DOI: 10.1016/j.bmc.2011.09.020 BindingDB Entry DOI: 10.7270/Q2Z89CTS
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