BDBM50357559 CHEMBL1915391

SMILES: OC(=O)[C@H]1Cc2c(CN1S(=O)(=O)c1ccc(Br)cc1)[nH]c1ccccc21

InChI Key: InChIKey=OGEDXWBIXQKGHZ-QGZVFWFLSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50357559   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Nitric Oxide Synthase, inducible (Mus musculus (mouse))	BDBM50357559 (CHEMBL1915391) Show SMILES OC(=O)[C@H]1Cc2c(CN1S(=O)(=O)c1ccc(Br)cc1)[nH]c1ccccc21 |r| Show InChI InChI=1S/C18H15BrN2O4S/c19-11-5-7-12(8-6-11)26(24,25)21-10-16-14(9-17(21)18(22)23)13-3-1-2-4-15(13)20-16/h1-8,17,20H,9-10H2,(H,22,23)/t17-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.61E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Hawai'i at Hilo Curated by ChEMBL					Assay Description Inhibition of iNOS-mediated nitric oxide production in LPS-stimulated mouse RAW 264.7 cells pretreated 15 mins before LPS challenge measured after 20...				Bioorg Med Chem 19: 6182-95 (2011) Article DOI: 10.1016/j.bmc.2011.09.020 BindingDB Entry DOI: 10.7270/Q2Z89CTS
					More data for this Ligand-Target Pair