BDBM50357637 CHEMBL1915677

SMILES: CN1C[C@@H](COc2cc(C)c(cc2C)C(=O)Nc2cc(CC(O)=O)ccc2Cl)Oc2ccccc12

InChI Key: InChIKey=SNYPIGRUBSRSAK-IBGZPJMESA-N

Data: 1 KI  1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50357637   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prostanoid IP receptor (Homo sapiens (Human))	BDBM50357637 (CHEMBL1915677) Show SMILES CN1C[C@@H](COc2cc(C)c(cc2C)C(=O)Nc2cc(CC(O)=O)ccc2Cl)Oc2ccccc12 |r| Show InChI InChI=1S/C27H27ClN2O5/c1-16-11-25(34-15-19-14-30(3)23-6-4-5-7-24(23)35-19)17(2)10-20(16)27(33)29-22-12-18(13-26(31)32)8-9-21(22)28/h4-12,19H,13-15H2,1-3H3,(H,29,33)(H,31,32)/t19-/m0/s1	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.80E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Ono Pharmaceutical Co., Ltd Curated by ChEMBL					Assay Description Displacement of [3H]Iloprost from human prostanoid IP receptor expressed in CHO cells after 30 mins by liquid scintillation counting				Bioorg Med Chem 19: 6935-48 (2011) Article DOI: 10.1016/j.bmc.2011.08.065 BindingDB Entry DOI: 10.7270/Q2K35V22
					More data for this Ligand-Target Pair
Prostanoid DP receptor (Mus musculus)	BDBM50357637 (CHEMBL1915677) Show SMILES CN1C[C@@H](COc2cc(C)c(cc2C)C(=O)Nc2cc(CC(O)=O)ccc2Cl)Oc2ccccc12 |r| Show InChI InChI=1S/C27H27ClN2O5/c1-16-11-25(34-15-19-14-30(3)23-6-4-5-7-24(23)35-19)17(2)10-20(16)27(33)29-22-12-18(13-26(31)32)8-9-21(22)28/h4-12,19H,13-15H2,1-3H3,(H,29,33)(H,31,32)/t19-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.10	n/a	n/a	n/a	n/a	n/a	n/a
Ono Pharmaceutical Co., Ltd Curated by ChEMBL					Assay Description Antagonist activity at mouse prostanoid DP receptor expressed in CHO cells assessed as inhibition of PGD2-induced intracellular cAMP production after...				Bioorg Med Chem 19: 6935-48 (2011) Article DOI: 10.1016/j.bmc.2011.08.065 BindingDB Entry DOI: 10.7270/Q2K35V22
					More data for this Ligand-Target Pair