BDBM50357771 CHEMBL1916408

SMILES: FC(F)(F)c1cc(cc(c1)C(F)(F)F)-c1nc(no1)N1CCc2nc[nH]c2C1

InChI Key: InChIKey=OCCUWVAUQWJIPS-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50357771   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sphingosine 1-phosphate receptor 1 (Homo sapiens (Human))	BDBM50357771 (CHEMBL1916408) Show SMILES FC(F)(F)c1cc(cc(c1)C(F)(F)F)-c1nc(no1)N1CCc2nc[nH]c2C1 Show InChI InChI=1S/C16H11F6N5O/c17-15(18,19)9-3-8(4-10(5-9)16(20,21)22)13-25-14(26-28-13)27-2-1-11-12(6-27)24-7-23-11/h3-5,7H,1-2,6H2,(H,23,24)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	406	n/a	n/a	n/a	n/a
Arena Pharmaceuticals Curated by ChEMBL					Assay Description Agonist activity at human S1P1 receptor expressed in HEK293 cells assessed as inhibition of forskolin-stimulated cAMP production after 1 hr by HTRF a...				Bioorg Med Chem Lett 21: 6013-8 (2011) Article DOI: 10.1016/j.bmcl.2011.05.110 BindingDB Entry DOI: 10.7270/Q24T6JSB
					More data for this Ligand-Target Pair