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SMILES: FC(F)(F)c1cc(cc(c1)C(F)(F)F)-c1nc(no1)-c1ccc2[nH]ccc2c1

InChI Key: InChIKey=MDONVTUDWMSWLJ-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50357774   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Sphingosine 1-phosphate receptor 1


(Homo sapiens (Human))		BDBM50357774
PNG
(CHEMBL1916411)
Show SMILES FC(F)(F)c1cc(cc(c1)C(F)(F)F)-c1nc(no1)-c1ccc2[nH]ccc2c1
Show InChI InChI=1S/C18H9F6N3O/c19-17(20,21)12-6-11(7-13(8-12)18(22,23)24)16-26-15(27-28-16)10-1-2-14-9(5-10)3-4-25-14/h1-8,25H
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n/an/an/an/a 75n/an/an/an/a



Arena Pharmaceuticals

Curated by ChEMBL


Assay Description
Agonist activity at human S1P1 receptor expressed in HEK293 cells assessed as inhibition of forskolin-stimulated cAMP production after 1 hr by HTRF a...

Bioorg Med Chem Lett 21: 6013-8 (2011)


Article DOI: 10.1016/j.bmcl.2011.05.110
BindingDB Entry DOI: 10.7270/Q24T6JSB
More data for this
Ligand-Target Pair