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SMILES: OC(=O)CCCn1ncc2CN(CCc12)c1noc(n1)-c1cc(cc(c1)C(F)(F)F)C(F)(F)F

InChI Key: InChIKey=WDRCXQAHTKCPJR-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50357778   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Sphingosine 1-phosphate receptor 1


(Homo sapiens (Human))		BDBM50357778
PNG
(CHEMBL1916556)
Show SMILES OC(=O)CCCn1ncc2CN(CCc12)c1noc(n1)-c1cc(cc(c1)C(F)(F)F)C(F)(F)F
Show InChI InChI=1S/C20H17F6N5O3/c21-19(22,23)13-6-11(7-14(8-13)20(24,25)26)17-28-18(29-34-17)30-5-3-15-12(10-30)9-27-31(15)4-1-2-16(32)33/h6-9H,1-5,10H2,(H,32,33)
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n/an/an/an/a 369n/an/an/an/a



Arena Pharmaceuticals

Curated by ChEMBL


Assay Description
Agonist activity at human S1P1 receptor expressed in HEK293 cells assessed as inhibition of forskolin-stimulated cAMP production after 1 hr by HTRF a...

Bioorg Med Chem Lett 21: 6013-8 (2011)


Article DOI: 10.1016/j.bmcl.2011.05.110
BindingDB Entry DOI: 10.7270/Q24T6JSB
More data for this
Ligand-Target Pair