BDBM50357794 CHEMBL1916571

SMILES: CC(C)Oc1ccc(cc1Br)-c1nc(no1)-c1ccc2N(CCc2c1)C(=O)CCC(O)=O

InChI Key: InChIKey=FTIMKOXSWLZXHU-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50357794   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sphingosine 1-phosphate receptor 1 (Homo sapiens (Human))	BDBM50357794 (CHEMBL1916571) Show SMILES CC(C)Oc1ccc(cc1Br)-c1nc(no1)-c1ccc2N(CCc2c1)C(=O)CCC(O)=O Show InChI InChI=1S/C23H22BrN3O5/c1-13(2)31-19-6-4-16(12-17(19)24)23-25-22(26-32-23)15-3-5-18-14(11-15)9-10-27(18)20(28)7-8-21(29)30/h3-6,11-13H,7-10H2,1-2H3,(H,29,30)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	4	n/a	n/a	n/a	n/a
Arena Pharmaceuticals Curated by ChEMBL					Assay Description Agonist activity at human S1P1 receptor expressed in HEK293 cells assessed as inhibition of forskolin-stimulated cAMP production after 1 hr by HTRF a...				Bioorg Med Chem Lett 21: 6013-8 (2011) Article DOI: 10.1016/j.bmcl.2011.05.110 BindingDB Entry DOI: 10.7270/Q24T6JSB
					More data for this Ligand-Target Pair