BDBM50357796 CHEMBL1916573

SMILES: OC(=O)CCC(=O)N1CCc2cc(ccc12)-c1noc(n1)-c1ccc(Cl)c(OC(F)(F)F)c1

InChI Key: InChIKey=FTAQOGGKROFSNT-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50357796   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sphingosine 1-phosphate receptor 1 (Homo sapiens (Human))	BDBM50357796 (CHEMBL1916573) Show SMILES OC(=O)CCC(=O)N1CCc2cc(ccc12)-c1noc(n1)-c1ccc(Cl)c(OC(F)(F)F)c1 Show InChI InChI=1S/C21H15ClF3N3O5/c22-14-3-1-13(10-16(14)32-21(23,24)25)20-26-19(27-33-20)12-2-4-15-11(9-12)7-8-28(15)17(29)5-6-18(30)31/h1-4,9-10H,5-8H2,(H,30,31)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	5.30	n/a	n/a	n/a	n/a
Arena Pharmaceuticals Curated by ChEMBL					Assay Description Agonist activity at human S1P1 receptor expressed in HEK293 cells assessed as inhibition of forskolin-stimulated cAMP production after 1 hr by HTRF a...				Bioorg Med Chem Lett 21: 6013-8 (2011) Article DOI: 10.1016/j.bmcl.2011.05.110 BindingDB Entry DOI: 10.7270/Q24T6JSB
					More data for this Ligand-Target Pair