null

SMILES: Cc1cc(OCCN2CCOCC2)ccc1-c1[n+]([O-])ccc2c(ccnc12)-c1ccc(F)cc1F

InChI Key: InChIKey=WIRJCECLJSKDCS-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50357895   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50357895 (CHEMBL1916352) Show SMILES Cc1cc(OCCN2CCOCC2)ccc1-c1[n+]([O-])ccc2c(ccnc12)-c1ccc(F)cc1F |(39.03,-36.8,;37.7,-37.57,;37.71,-39.11,;36.38,-39.89,;36.38,-41.43,;35.05,-42.2,;33.71,-41.44,;32.38,-42.21,;31.05,-41.44,;29.73,-42.21,;29.72,-43.75,;31.06,-44.52,;32.4,-43.75,;35.04,-39.12,;35.04,-37.58,;36.37,-36.81,;36.37,-35.28,;35.03,-34.51,;33.7,-35.28,;35.04,-32.96,;36.37,-32.19,;37.7,-32.96,;39.03,-32.18,;40.37,-32.96,;40.37,-34.51,;39.03,-35.27,;37.7,-34.5,;39.03,-30.65,;37.7,-29.88,;37.7,-28.35,;39.04,-27.57,;39.04,-26.03,;40.37,-28.34,;40.37,-29.88,;41.7,-30.65,)| Show InChI InChI=1S/C27H25F2N3O3/c1-18-16-20(35-15-12-31-10-13-34-14-11-31)3-5-21(18)27-26-24(7-9-32(27)33)22(6-8-30-26)23-4-2-19(28)17-25(23)29/h2-9,16-17H,10-15H2,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	422	n/a	n/a	n/a	n/a	n/a	n/a
Rhône-Poulenc Rorer Curated by ChEMBL					Assay Description Inhibition of human p38alpha MAP kinase after 1 hr by FRET analysis				J Med Chem 54: 7899-910 (2011) Article DOI: 10.1021/jm200975u BindingDB Entry DOI: 10.7270/Q2MW2HKR
					More data for this Ligand-Target Pair