BindingDB logo
myBDB logout

null

SMILES: COc1ccccc1-c1ccnc2c(-c3c(F)cccc3F)[n+]([O-])ccc12

InChI Key: InChIKey=KROWIURGYUBEKL-UHFFFAOYSA-N

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50357898   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Mitogen-activated protein kinase 14


(Homo sapiens (Human))		BDBM50357898
PNG
(CHEMBL1916355)
Show SMILES COc1ccccc1-c1ccnc2c(-c3c(F)cccc3F)[n+]([O-])ccc12 |(15.24,2.65,;16.58,1.89,;17.91,2.66,;17.9,4.2,;19.24,4.97,;20.58,4.2,;20.58,2.66,;19.24,1.89,;19.24,.36,;20.58,-.42,;20.58,-1.96,;19.23,-2.73,;17.9,-1.96,;16.57,-2.74,;16.58,-4.27,;15.24,-5.04,;13.91,-4.27,;15.25,-6.58,;16.58,-7.35,;17.92,-6.57,;17.91,-5.03,;19.24,-4.25,;15.24,-1.96,;13.91,-2.73,;15.24,-.42,;16.57,.35,;17.91,-.41,)|
Show InChI InChI=1S/C21H14F2N2O2/c1-27-18-8-3-2-5-14(18)13-9-11-24-20-15(13)10-12-25(26)21(20)19-16(22)6-4-7-17(19)23/h2-12H,1H3
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 77n/an/an/an/an/an/a



Rhône-Poulenc Rorer

Curated by ChEMBL


Assay Description
Inhibition of human p38alpha MAP kinase after 1 hr by FRET analysis

J Med Chem 54: 7899-910 (2011)


Article DOI: 10.1021/jm200975u
BindingDB Entry DOI: 10.7270/Q2MW2HKR
More data for this
Ligand-Target Pair