BDBM50357899 CHEMBL1916356

SMILES: [O-][n+]1ccc2c(ccnc2c1-c1c(Cl)cccc1Cl)-c1cccc(c1)C(F)(F)F

InChI Key: InChIKey=HSJWZSREZDAXNC-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50357899   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50357899 (CHEMBL1916356) Show SMILES [O-][n+]1ccc2c(ccnc2c1-c1c(Cl)cccc1Cl)-c1cccc(c1)C(F)(F)F |(25.31,-3.57,;26.64,-2.8,;26.64,-1.25,;27.97,-.48,;29.31,-1.25,;30.64,-.47,;31.98,-1.25,;31.98,-2.8,;30.64,-3.56,;29.31,-2.79,;27.98,-3.57,;27.98,-5.1,;26.65,-5.87,;25.31,-5.1,;26.65,-7.41,;27.98,-8.18,;29.32,-7.4,;29.31,-5.86,;30.64,-5.09,;30.64,1.06,;31.98,1.83,;31.98,3.37,;30.64,4.14,;29.31,3.36,;29.31,1.83,;27.97,4.13,;27.96,5.67,;26.64,3.35,;26.63,4.9,)| Show InChI InChI=1S/C21H11Cl2F3N2O/c22-16-5-2-6-17(23)18(16)20-19-15(8-10-28(20)29)14(7-9-27-19)12-3-1-4-13(11-12)21(24,25)26/h1-11H	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Rhône-Poulenc Rorer Curated by ChEMBL					Assay Description Inhibition of human p38alpha MAP kinase after 1 hr by FRET analysis				J Med Chem 54: 7899-910 (2011) Article DOI: 10.1021/jm200975u BindingDB Entry DOI: 10.7270/Q2MW2HKR
					More data for this Ligand-Target Pair