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SMILES: O=C(Nc1ccc(cc1)N1S(=O)(=O)c2ccccc2S1(=O)=O)c1ccco1

InChI Key: InChIKey=GHPJWCBZTHWCLX-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50358180   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Metabotropic glutamate receptor 4


(Homo sapiens (Human))		BDBM50358180
PNG
(CHEMBL1921852)
Show SMILES O=C(Nc1ccc(cc1)N1S(=O)(=O)c2ccccc2S1(=O)=O)c1ccco1
Show InChI InChI=1S/C17H12N2O6S2/c20-17(14-4-3-11-25-14)18-12-7-9-13(10-8-12)19-26(21,22)15-5-1-2-6-16(15)27(19,23)24/h1-11H,(H,18,20)
PDB

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PC sid
UniChem

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PubMed
n/an/an/an/a 226n/an/an/an/a



Vanderbilt University Medical Center

Curated by ChEMBL


Assay Description
Positive allosteric modulator activity at human mGlu4 receptor expressed in CHO cells expressing Gqi5 by calcium mobilization assay

J Med Chem 54: 7639-47 (2011)


Article DOI: 10.1021/jm200956q
BindingDB Entry DOI: 10.7270/Q25Q4WHD
More data for this
Ligand-Target Pair