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BDBM50358183 CHEMBL1921948

SMILES: Fc1cccc(n1)C(=O)Nc1ccc(cc1)N1S(=O)(=O)c2ccccc2S1(=O)=O

InChI Key: InChIKey=CODVTIMDGLQNFG-UHFFFAOYSA-N

Data: 1 EC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50358183   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Metabotropic glutamate receptor 4 (mGluR4)


(Homo sapiens (Human))
BDBM50358183
PNG
(CHEMBL1921948)
Show SMILES Fc1cccc(n1)C(=O)Nc1ccc(cc1)N1S(=O)(=O)c2ccccc2S1(=O)=O
Show InChI InChI=1S/C18H12FN3O5S2/c19-17-7-3-4-14(21-17)18(23)20-12-8-10-13(11-9-12)22-28(24,25)15-5-1-2-6-16(15)29(22,26)27/h1-11H,(H,20,23)
UniProtKB/SwissProt

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CHEMBL
PC cid
PC sid
UniChem

Patents

Article
PubMed
n/an/an/an/a 1.80E+3n/an/an/an/a



Vanderbilt University Medical Center

Curated by ChEMBL


Assay Description
Positive allosteric modulator activity at human mGlu4 receptor expressed in CHO cells expressing Gqi5 by calcium mobilization assay


J Med Chem 54: 7639-47 (2011)


Article DOI: 10.1021/jm200956q
BindingDB Entry DOI: 10.7270/Q25Q4WHD
More data for this
Ligand-Target Pair