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BDBM50358185 CHEMBL1921955

SMILES: O=S1(=O)N(c2ccc(NCc3ccccn3)cc2)S(=O)(=O)c2ccccc12

InChI Key: InChIKey=KYHPUGUHKOVFGX-UHFFFAOYSA-N

Data: 1 EC50

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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50358185   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Metabotropic glutamate receptor 4 (mGluR4)


(Homo sapiens (Human))
BDBM50358185
PNG
(CHEMBL1921955)
Show SMILES O=S1(=O)N(c2ccc(NCc3ccccn3)cc2)S(=O)(=O)c2ccccc12
Show InChI InChI=1S/C18H15N3O4S2/c22-26(23)17-6-1-2-7-18(17)27(24,25)21(26)16-10-8-14(9-11-16)20-13-15-5-3-4-12-19-15/h1-12,20H,13H2
UniProtKB/SwissProt

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GoogleScholar
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CHEMBL
PC cid
PC sid
UniChem

Patents

Article
PubMed
n/an/an/an/a 1.80E+3n/an/an/an/a



Vanderbilt University Medical Center

Curated by ChEMBL


Assay Description
Positive allosteric modulator activity at human mGlu4 receptor expressed in CHO cells expressing Gqi5 by calcium mobilization assay


J Med Chem 54: 7639-47 (2011)


Article DOI: 10.1021/jm200956q
BindingDB Entry DOI: 10.7270/Q25Q4WHD
More data for this
Ligand-Target Pair