BDBM50358186 CHEMBL1921956

SMILES: O=S1(=O)N(c2ccc(NC3(CC3)c3ccccn3)cc2)S(=O)(=O)c2ccccc12

InChI Key: InChIKey=ZAMGJXDALMAKDP-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50358186   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Metabotropic glutamate receptor 4 (mGluR4) (Homo sapiens (Human))	BDBM50358186 (CHEMBL1921956) Show SMILES O=S1(=O)N(c2ccc(NC3(CC3)c3ccccn3)cc2)S(=O)(=O)c2ccccc12 Show InChI InChI=1S/C20H17N3O4S2/c24-28(25)17-5-1-2-6-18(17)29(26,27)23(28)16-10-8-15(9-11-16)22-20(12-13-20)19-7-3-4-14-21-19/h1-11,14,22H,12-13H2	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	6.40E+3	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Positive allosteric modulator activity at human mGlu4 receptor expressed in CHO cells expressing Gqi5 by calcium mobilization assay				J Med Chem 54: 7639-47 (2011) Article DOI: 10.1021/jm200956q BindingDB Entry DOI: 10.7270/Q25Q4WHD
					More data for this Ligand-Target Pair