BDBM50358254 CHEMBL1922233

SMILES: COc1ccc(cc1)C(=O)Nc1cccc(C(O)=O)c1NC(=O)c1ccc(cc1)N1CCCN(C)CC1

InChI Key: InChIKey=SQTIAXOMFTYLLF-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50358254   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Coagulation factor X (Homo sapiens (Human))	BDBM50358254 (CHEMBL1922233) Show SMILES COc1ccc(cc1)C(=O)Nc1cccc(C(O)=O)c1NC(=O)c1ccc(cc1)N1CCCN(C)CC1 Show InChI InChI=1S/C28H30N4O5/c1-31-15-4-16-32(18-17-31)21-11-7-19(8-12-21)27(34)30-25-23(28(35)36)5-3-6-24(25)29-26(33)20-9-13-22(37-2)14-10-20/h3,5-14H,4,15-18H2,1-2H3,(H,29,33)(H,30,34)(H,35,36)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	99.2	n/a	n/a	n/a	n/a	n/a	n/a
Astellas Pharma Inc Curated by ChEMBL					Assay Description Inhibition of human factor 10A using chromogenic substrate S2222 by fluorometric analysis				J Med Chem 54: 8051-65 (2011) Article DOI: 10.1021/jm200868m BindingDB Entry DOI: 10.7270/Q2D50ND9
					More data for this Ligand-Target Pair