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BDBM50358254 CHEMBL1922233

SMILES: COc1ccc(cc1)C(=O)Nc1cccc(C(O)=O)c1NC(=O)c1ccc(cc1)N1CCCN(C)CC1

InChI Key: InChIKey=SQTIAXOMFTYLLF-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50358254   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Coagulation factor X


(Homo sapiens (Human))
BDBM50358254
PNG
(CHEMBL1922233)
Show SMILES COc1ccc(cc1)C(=O)Nc1cccc(C(O)=O)c1NC(=O)c1ccc(cc1)N1CCCN(C)CC1
Show InChI InChI=1S/C28H30N4O5/c1-31-15-4-16-32(18-17-31)21-11-7-19(8-12-21)27(34)30-25-23(28(35)36)5-3-6-24(25)29-26(33)20-9-13-22(37-2)14-10-20/h3,5-14H,4,15-18H2,1-2H3,(H,29,33)(H,30,34)(H,35,36)
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Article
PubMed
n/an/a 99.2n/an/an/an/an/an/a



Astellas Pharma Inc

Curated by ChEMBL


Assay Description
Inhibition of human factor 10A using chromogenic substrate S2222 by fluorometric analysis


J Med Chem 54: 8051-65 (2011)


Article DOI: 10.1021/jm200868m
BindingDB Entry DOI: 10.7270/Q2D50ND9
More data for this
Ligand-Target Pair