BDBM50358258 CHEMBL1922227

SMILES: COc1ccc(cc1)C(=O)Nc1ccccc1C(=O)Nc1ccc(cc1)N1CCCN(C)CC1

InChI Key: InChIKey=HIPZERUQFQVVJB-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50358258   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Coagulation factor X (Homo sapiens (Human))	BDBM50358258 (CHEMBL1922227) Show SMILES COc1ccc(cc1)C(=O)Nc1ccccc1C(=O)Nc1ccc(cc1)N1CCCN(C)CC1 Show InChI InChI=1S/C27H30N4O3/c1-30-16-5-17-31(19-18-30)22-12-10-21(11-13-22)28-27(33)24-6-3-4-7-25(24)29-26(32)20-8-14-23(34-2)15-9-20/h3-4,6-15H,5,16-19H2,1-2H3,(H,28,33)(H,29,32)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	539	n/a	n/a	n/a	n/a	n/a	n/a
Astellas Pharma Inc Curated by ChEMBL					Assay Description Inhibition of human factor 10A using chromogenic substrate S2222 by fluorometric analysis				J Med Chem 54: 8051-65 (2011) Article DOI: 10.1021/jm200868m BindingDB Entry DOI: 10.7270/Q2D50ND9
					More data for this Ligand-Target Pair