BDBM50358261 CHEMBL1922230

SMILES: COc1ccc(cc1)C(=O)Nc1ccc(OC)cc1NC(=O)c1ccc(cc1)N1CCCN(C)CC1

InChI Key: InChIKey=SQFMGRZZHHSOMM-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50358261   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Coagulation factor X (Homo sapiens (Human))	BDBM50358261 (CHEMBL1922230) Show SMILES COc1ccc(cc1)C(=O)Nc1ccc(OC)cc1NC(=O)c1ccc(cc1)N1CCCN(C)CC1 Show InChI InChI=1S/C28H32N4O4/c1-31-15-4-16-32(18-17-31)22-9-5-20(6-10-22)28(34)30-26-19-24(36-3)13-14-25(26)29-27(33)21-7-11-23(35-2)12-8-21/h5-14,19H,4,15-18H2,1-3H3,(H,29,33)(H,30,34)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	73.4	n/a	n/a	n/a	n/a	n/a	n/a
Astellas Pharma Inc Curated by ChEMBL					Assay Description Inhibition of human factor 10A using chromogenic substrate S2222 by fluorometric analysis				J Med Chem 54: 8051-65 (2011) Article DOI: 10.1021/jm200868m BindingDB Entry DOI: 10.7270/Q2D50ND9
					More data for this Ligand-Target Pair