BDBM50358271 CHEMBL1922338

SMILES: CN1CCCN(CC1)c1ccc(cc1)C(=O)Nc1c(O)cccc1NC(=O)c1ccc(F)cc1

InChI Key: InChIKey=IFVIZWYRFUIABK-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50358271   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Coagulation factor X (Homo sapiens (Human))	BDBM50358271 (CHEMBL1922338) Show SMILES CN1CCCN(CC1)c1ccc(cc1)C(=O)Nc1c(O)cccc1NC(=O)c1ccc(F)cc1 Show InChI InChI=1S/C26H27FN4O3/c1-30-14-3-15-31(17-16-30)21-12-8-19(9-13-21)26(34)29-24-22(4-2-5-23(24)32)28-25(33)18-6-10-20(27)11-7-18/h2,4-13,32H,3,14-17H2,1H3,(H,28,33)(H,29,34)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	349	n/a	n/a	n/a	n/a	n/a	n/a
Astellas Pharma Inc Curated by ChEMBL					Assay Description Inhibition of human factor 10A using chromogenic substrate S2222 by fluorometric analysis				J Med Chem 54: 8051-65 (2011) Article DOI: 10.1021/jm200868m BindingDB Entry DOI: 10.7270/Q2D50ND9
					More data for this Ligand-Target Pair