BDBM50358433 CHEMBL1922899

SMILES: Fc1cccc(Oc2ccc(Nc3ncnc4cc[nH]c34)cc2Cl)c1

InChI Key: InChIKey=LJQVSABKPVFCTG-UHFFFAOYSA-N

Data: 1 IC50

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Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50358433   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Receptor tyrosine-protein kinase erbB-2 (Homo sapiens (Human))	BDBM50358433 (CHEMBL1922899) Show SMILES Fc1cccc(Oc2ccc(Nc3ncnc4cc[nH]c34)cc2Cl)c1 Show InChI InChI=1S/C18H12ClFN4O/c19-14-9-12(24-18-17-15(6-7-21-17)22-10-23-18)4-5-16(14)25-13-3-1-2-11(20)8-13/h1-10,21H,(H,22,23,24)	PDB MMDB UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company Limited Curated by ChEMBL					Assay Description Inhibition of human N-terminus peptide (DYKDDDD)-tagged HER2 expressed in baculovirus infected insect cells using [gamma-32P]ATP as substrate after 6...				J Med Chem 54: 8030-50 (2011) Article DOI: 10.1021/jm2008634 BindingDB Entry DOI: 10.7270/Q23R0T93
					More data for this Ligand-Target Pair