BDBM50358447 CHEMBL1923002

SMILES: Cc1ccc(Oc2ccc(Nc3ncnc4cc[nH]c34)cc2C)cn1

InChI Key: InChIKey=SZVAKAGCAKQORO-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50358447   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Receptor tyrosine-protein kinase erbB-2 (Homo sapiens (Human))	BDBM50358447 (CHEMBL1923002) Show SMILES Cc1ccc(Oc2ccc(Nc3ncnc4cc[nH]c34)cc2C)cn1 Show InChI InChI=1S/C19H17N5O/c1-12-9-14(24-19-18-16(7-8-20-18)22-11-23-19)4-6-17(12)25-15-5-3-13(2)21-10-15/h3-11,20H,1-2H3,(H,22,23,24)	PDB MMDB UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	60	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company Limited Curated by ChEMBL					Assay Description Inhibition of human N-terminus peptide (DYKDDDD)-tagged HER2 expressed in baculovirus infected insect cells using [gamma-32P]ATP as substrate after 6...				J Med Chem 54: 8030-50 (2011) Article DOI: 10.1021/jm2008634 BindingDB Entry DOI: 10.7270/Q23R0T93
					More data for this Ligand-Target Pair