null

SMILES: COc1ccc(Oc2ncc(Cl)c(Nc3ccccc3C(N)=O)n2)cc1

InChI Key: InChIKey=DEPFXQSAHGKYPV-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50358497   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase 8 (Homo sapiens (Human))	BDBM50358497 (CHEMBL1923217) Show SMILES COc1ccc(Oc2ncc(Cl)c(Nc3ccccc3C(N)=O)n2)cc1 Show InChI InChI=1S/C18H15ClN4O3/c1-25-11-6-8-12(9-7-11)26-18-21-10-14(19)17(23-18)22-15-5-3-2-4-13(15)16(20)24/h2-10H,1H3,(H2,20,24)(H,21,22,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Inhibition of JNK1 using biotinylated-ATF2 as substrate by HTRF assay				Bioorg Med Chem Lett 21: 7072-5 (2011) Article DOI: 10.1016/j.bmcl.2011.09.090 BindingDB Entry DOI: 10.7270/Q2V69K0W
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 10 (Homo sapiens (Human))	BDBM50358497 (CHEMBL1923217) Show SMILES COc1ccc(Oc2ncc(Cl)c(Nc3ccccc3C(N)=O)n2)cc1 Show InChI InChI=1S/C18H15ClN4O3/c1-25-11-6-8-12(9-7-11)26-18-21-10-14(19)17(23-18)22-15-5-3-2-4-13(15)16(20)24/h2-10H,1H3,(H2,20,24)(H,21,22,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Inhibition of JNK3 using biotinylated-ATF2 as substrate by HTRF assay				Bioorg Med Chem Lett 21: 7072-5 (2011) Article DOI: 10.1016/j.bmcl.2011.09.090 BindingDB Entry DOI: 10.7270/Q2V69K0W
					More data for this Ligand-Target Pair