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SMILES: COc1ccc(Oc2cc(Nc3cc(OC)ccc3C(N)=O)c(cn2)C(F)(F)F)cc1

InChI Key: InChIKey=VLAOHGRMNLKXML-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50358502   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Mitogen-activated protein kinase 10


(Homo sapiens (Human))		BDBM50358502
PNG
(CHEMBL1923211)
Show SMILES COc1ccc(Oc2cc(Nc3cc(OC)ccc3C(N)=O)c(cn2)C(F)(F)F)cc1
Show InChI InChI=1S/C21H18F3N3O4/c1-29-12-3-5-13(6-4-12)31-19-10-18(16(11-26-19)21(22,23)24)27-17-9-14(30-2)7-8-15(17)20(25)28/h3-11H,1-2H3,(H2,25,28)(H,26,27)
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MMDB

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Article
PubMed
n/an/a 17n/an/an/an/an/an/a



The Scripps Research Institute

Curated by ChEMBL


Assay Description
Inhibition of JNK3 using biotinylated-ATF2 as substrate by HTRF assay

Bioorg Med Chem Lett 21: 7072-5 (2011)


Article DOI: 10.1016/j.bmcl.2011.09.090
BindingDB Entry DOI: 10.7270/Q2V69K0W
More data for this
Ligand-Target Pair