null

SMILES: COc1ccc(Oc2cc(Nc3ccccc3C(N)=O)c(F)cn2)cc1

InChI Key: InChIKey=LRUPHJAQKSRDNC-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50358528   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase 8 (Homo sapiens (Human))	BDBM50358528 (CHEMBL1923186) Show SMILES COc1ccc(Oc2cc(Nc3ccccc3C(N)=O)c(F)cn2)cc1 Show InChI InChI=1S/C19H16FN3O3/c1-25-12-6-8-13(9-7-12)26-18-10-17(15(20)11-22-18)23-16-5-3-2-4-14(16)19(21)24/h2-11H,1H3,(H2,21,24)(H,22,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	26	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Inhibition of JNK1 using biotinylated-ATF2 as substrate by HTRF assay				Bioorg Med Chem Lett 21: 7072-5 (2011) Article DOI: 10.1016/j.bmcl.2011.09.090 BindingDB Entry DOI: 10.7270/Q2V69K0W
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 10 (Homo sapiens (Human))	BDBM50358528 (CHEMBL1923186) Show SMILES COc1ccc(Oc2cc(Nc3ccccc3C(N)=O)c(F)cn2)cc1 Show InChI InChI=1S/C19H16FN3O3/c1-25-12-6-8-13(9-7-12)26-18-10-17(15(20)11-22-18)23-16-5-3-2-4-14(16)19(21)24/h2-11H,1H3,(H2,21,24)(H,22,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	48	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Inhibition of JNK3 using biotinylated-ATF2 as substrate by HTRF assay				Bioorg Med Chem Lett 21: 7072-5 (2011) Article DOI: 10.1016/j.bmcl.2011.09.090 BindingDB Entry DOI: 10.7270/Q2V69K0W
					More data for this Ligand-Target Pair