null

SMILES: COc1cccc(CN(C)C(=O)c2cc3ccc(cc3n2C)-c2cn[nH]c2)c1

InChI Key: InChIKey=WHYNQEXITVKVEG-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50358699   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Rho-associated protein kinase 1 (Homo sapiens (Human))	BDBM50358699 (CHEMBL1922030) Show SMILES COc1cccc(CN(C)C(=O)c2cc3ccc(cc3n2C)-c2cn[nH]c2)c1 Show InChI InChI=1S/C22H22N4O2/c1-25(14-15-5-4-6-19(9-15)28-3)22(27)21-11-17-8-7-16(10-20(17)26(21)2)18-12-23-24-13-18/h4-13H,14H2,1-3H3,(H,23,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Inhibition of ROCK1				Bioorg Med Chem Lett 21: 7113-8 (2011) Article DOI: 10.1016/j.bmcl.2011.09.084 BindingDB Entry DOI: 10.7270/Q2F1905N
					More data for this Ligand-Target Pair
Rho-associated protein kinase 2 (Homo sapiens (Human))	BDBM50358699 (CHEMBL1922030) Show SMILES COc1cccc(CN(C)C(=O)c2cc3ccc(cc3n2C)-c2cn[nH]c2)c1 Show InChI InChI=1S/C22H22N4O2/c1-25(14-15-5-4-6-19(9-15)28-3)22(27)21-11-17-8-7-16(10-20(17)26(21)2)18-12-23-24-13-18/h4-13H,14H2,1-3H3,(H,23,24)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Inhibition of ROCK2				Bioorg Med Chem Lett 21: 7113-8 (2011) Article DOI: 10.1016/j.bmcl.2011.09.084 BindingDB Entry DOI: 10.7270/Q2F1905N
					More data for this Ligand-Target Pair