BDBM50358778 CHEMBL1922616
SMILES: CNc1nn2c(N)c(Cl)c(C)nc2c1S(=O)(=O)c1ccccc1
InChI Key: InChIKey=KYZVFKJOEFOFKM-UHFFFAOYSA-N
Data: 1 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
5-hydroxytryptamine receptor 6 (Homo sapiens (Human)) | BDBM50358778 (CHEMBL1922616) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 0.140 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Chemical Diversity Research Institute Curated by ChEMBL | Assay Description Inhibition of human recombinant 5-HT6 receptor expressed in human HEK293 cells assessed as inhibition of serotonin-induced cAMP accumulation | J Med Chem 54: 8161-73 (2011) Article DOI: 10.1021/jm201079g BindingDB Entry DOI: 10.7270/Q2X067F0 | |||||||||||
More data for this Ligand-Target Pair |