BDBM50358879 CHEMBL1923464

SMILES: CN1CCN(CC1)C(=O)CN1CCC[C@H](NS(=O)(=O)c2ccc3cc(Cl)ccc3c2)C1=O

InChI Key: InChIKey=CQOWSVYMXAKODA-FQEVSTJZSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50358879   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Coagulation factor X (Homo sapiens (Human))	BDBM50358879 (CHEMBL1923464) Show SMILES CN1CCN(CC1)C(=O)CN1CCC[C@H](NS(=O)(=O)c2ccc3cc(Cl)ccc3c2)C1=O |r| Show InChI InChI=1S/C22H27ClN4O4S/c1-25-9-11-26(12-10-25)21(28)15-27-8-2-3-20(22(27)29)24-32(30,31)19-7-5-16-13-18(23)6-4-17(16)14-19/h4-7,13-14,20,24H,2-3,8-12,15H2,1H3/t20-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.96E+3	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company Curated by ChEMBL					Assay Description Inhibition of human factor 10a using phenyl-Ile-Glu-Gly-Arg-pNA as substrate preincubated for 3 mins prior to substrate addition by spectrophotometry				Bioorg Med Chem Lett 21: 7516-21 (2011) Article DOI: 10.1016/j.bmcl.2011.06.098 BindingDB Entry DOI: 10.7270/Q2MK6DBS
					More data for this Ligand-Target Pair