BDBM50358884 CHEMBL1923469

SMILES: CC(=O)N1CC2CC(C1)CN(C2)C(=O)CN1CCC[C@H](NS(=O)(=O)c2ccc3cc(Cl)ccc3c2)C1=O

InChI Key: InChIKey=UWIZWPSBMKSPLR-MORLXBONSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50358884   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Coagulation factor X (Homo sapiens (Human))	BDBM50358884 (CHEMBL1923469) Show SMILES CC(=O)N1CC2CC(C1)CN(C2)C(=O)CN1CCC[C@H](NS(=O)(=O)c2ccc3cc(Cl)ccc3c2)C1=O |r| Show InChI InChI=1S/C26H31ClN4O5S/c1-17(32)30-12-18-9-19(13-30)15-31(14-18)25(33)16-29-8-2-3-24(26(29)34)28-37(35,36)23-7-5-20-10-22(27)6-4-21(20)11-23/h4-7,10-11,18-19,24,28H,2-3,8-9,12-16H2,1H3/t18?,19?,24-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company Curated by ChEMBL					Assay Description Inhibition of human factor 10a using phenyl-Ile-Glu-Gly-Arg-pNA as substrate preincubated for 3 mins prior to substrate addition by spectrophotometry				Bioorg Med Chem Lett 21: 7516-21 (2011) Article DOI: 10.1016/j.bmcl.2011.06.098 BindingDB Entry DOI: 10.7270/Q2MK6DBS
					More data for this Ligand-Target Pair