BDBM50358885 CHEMBL1923470

SMILES: NC(=O)N1CC2CC(C1)CN(C2)C(=O)CN1CCC[C@H](NS(=O)(=O)c2ccc3cc(Cl)ccc3c2)C1=O

InChI Key: InChIKey=GGYBEPXKHZMBBU-XWTGJVNOSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50358885   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Coagulation factor X (Homo sapiens (Human))	BDBM50358885 (CHEMBL1923470) Show SMILES NC(=O)N1CC2CC(C1)CN(C2)C(=O)CN1CCC[C@H](NS(=O)(=O)c2ccc3cc(Cl)ccc3c2)C1=O |r| Show InChI InChI=1S/C25H30ClN5O5S/c26-20-5-3-19-10-21(6-4-18(19)9-20)37(35,36)28-22-2-1-7-29(24(22)33)15-23(32)30-11-16-8-17(12-30)14-31(13-16)25(27)34/h3-6,9-10,16-17,22,28H,1-2,7-8,11-15H2,(H2,27,34)/t16?,17?,22-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company Curated by ChEMBL					Assay Description Inhibition of human factor 10a using phenyl-Ile-Glu-Gly-Arg-pNA as substrate preincubated for 3 mins prior to substrate addition by spectrophotometry				Bioorg Med Chem Lett 21: 7516-21 (2011) Article DOI: 10.1016/j.bmcl.2011.06.098 BindingDB Entry DOI: 10.7270/Q2MK6DBS
					More data for this Ligand-Target Pair