BDBM50358889 CHEMBL1923563

SMILES: Nc1[nH]ncc1C(=O)N1CC2CC(CN(C2)C(=O)CN2CCC[C@H](NS(=O)(=O)c3ccc4cc(Cl)ccc4c3)C2=O)C1

InChI Key: InChIKey=ANLHUSPUHZKQAT-XCNDVJPKSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50358889   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Coagulation factor X (Homo sapiens (Human))	BDBM50358889 (CHEMBL1923563) Show SMILES Nc1[nH]ncc1C(=O)N1CC2CC(CN(C2)C(=O)CN2CCC[C@H](NS(=O)(=O)c3ccc4cc(Cl)ccc4c3)C2=O)C1 |r| Show InChI InChI=1S/C28H32ClN7O5S/c29-21-5-3-20-10-22(6-4-19(20)9-21)42(40,41)33-24-2-1-7-34(28(24)39)16-25(37)35-12-17-8-18(13-35)15-36(14-17)27(38)23-11-31-32-26(23)30/h3-6,9-11,17-18,24,33H,1-2,7-8,12-16H2,(H3,30,31,32)/t17?,18?,24-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company Curated by ChEMBL					Assay Description Inhibition of human factor 10a using phenyl-Ile-Glu-Gly-Arg-pNA as substrate preincubated for 3 mins prior to substrate addition by spectrophotometry				Bioorg Med Chem Lett 21: 7516-21 (2011) Article DOI: 10.1016/j.bmcl.2011.06.098 BindingDB Entry DOI: 10.7270/Q2MK6DBS
					More data for this Ligand-Target Pair