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SMILES: CC(C)(C)c1cc(C(=O)N2CCNS(=O)(=O)CC2)c(NC(=O)Nc2cccc3ccccc23)s1

InChI Key: InChIKey=XHMFMQGWODYKDN-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50359338   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Mitogen-activated protein kinase 14


(Homo sapiens (Human))		BDBM50359338
PNG
(CHEMBL1929218)
Show SMILES CC(C)(C)c1cc(C(=O)N2CCNS(=O)(=O)CC2)c(NC(=O)Nc2cccc3ccccc23)s1
Show InChI InChI=1S/C24H28N4O4S2/c1-24(2,3)20-15-18(22(29)28-12-11-25-34(31,32)14-13-28)21(33-20)27-23(30)26-19-10-6-8-16-7-4-5-9-17(16)19/h4-10,15,25H,11-14H2,1-3H3,(H2,26,27,30)
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n/an/a 110n/an/an/an/an/an/a



Ansaris

Curated by ChEMBL


Assay Description
Inhibition of p38alpha assessed as [33P]gamma-ATP incorporation into GST-ATF2 substrate preincubated for 20 mins before substrate addition measured a...

Bioorg Med Chem Lett 21: 7155-65 (2011)


Article DOI: 10.1016/j.bmcl.2011.09.078
BindingDB Entry DOI: 10.7270/Q2NC61NH
More data for this
Ligand-Target Pair